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Mapping Genetically Compensatory Pathways from Synthetic Lethal Interactions in Yeast

BACKGROUND: Synthetic lethal genetic interaction analysis has been successfully applied to predicting the functions of genes and their pathway identities. In the context of synthetic lethal interaction data alone, the global similarity of synthetic lethal interaction patterns between two genes is us...

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Detalles Bibliográficos
Autores principales: Ma, Xiaotu, Tarone, Aaron M., Li, Wenyuan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275788/
https://www.ncbi.nlm.nih.gov/pubmed/18398455
http://dx.doi.org/10.1371/journal.pone.0001922