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Structure of Germline Immunoglobulin Heavy-Chain γ1 Transcripts in Interleukin 4 Treated Mouse Spleen Cells
Antibody class switching is mediated by a DNA recombination event that replaces the Cμ gene with one of the other heavy (H) chain constant region (C(H)) genes located 3' to the Cμ gene. The regulation of this process is essential to the immune response because different C(H) regions provide dif...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Hindawi Publishing Corporation
1990
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275814/ https://www.ncbi.nlm.nih.gov/pubmed/1726553 http://dx.doi.org/10.1155/1990/47659 |