Cargando…
Structure of Germline Immunoglobulin Heavy-Chain γ1 Transcripts in Interleukin 4 Treated Mouse Spleen Cells
Antibody class switching is mediated by a DNA recombination event that replaces the Cμ gene with one of the other heavy (H) chain constant region (C(H)) genes located 3' to the Cμ gene. The regulation of this process is essential to the immune response because different C(H) regions provide dif...
Autores principales: | Xu, Minzhen, Stavnezer, Janet |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
1990
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275814/ https://www.ncbi.nlm.nih.gov/pubmed/1726553 http://dx.doi.org/10.1155/1990/47659 |
Ejemplares similares
-
The 3′ end of the heavy chain constant region locus enhances germline transcription and switch recombination of the four γ genes
por: Dunnick, Wesley A., et al.
Publicado: (2005) -
Immunoglobulin Analysis Tool: A Novel Tool for the Analysis of Human and Mouse Heavy and Light Chain Transcripts
por: Rogosch, Tobias, et al.
Publicado: (2012) -
Somatic variation precedes extensive diversification of germline sequences and combinatorial joining in the evolution of immunoglobulin heavy chain diversity
Publicado: (1993) -
Biallelic Germline Transcription at the κ Immunoglobulin Locus
por: Singh, Nandita, et al.
Publicado: (2003) -
Immunoglobulin Heavy Chain Exclusion in the Shark
por: Malecek, Karolina, et al.
Publicado: (2008)