Immunoglobulin λ Gene Rearrangement Can Precede κ Gene Rearrangement

Immunoglobulin genes are generated during differentiation of B lymphocytes by joining gene segments. A mouse pre-B cell contains a functional immunoglobulin heavy-chain gene, but no light-chain gene. Although there is only one heavy-chain locus, there are two lightchain loci: κ and λ.It has been rep...

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Detalles Bibliográficos
Autores principales: Berg, Jörg, Mcdowell, Mindy, Jäck, Hans-Martin, Wabl, Matthias
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1990
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275820/
https://www.ncbi.nlm.nih.gov/pubmed/2136205
http://dx.doi.org/10.1155/1990/56014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275820/
https://www.ncbi.nlm.nih.gov/pubmed/2136205
http://dx.doi.org/10.1155/1990/56014

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