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Immunoglobulin λ Gene Rearrangement Can Precede κ Gene Rearrangement

Immunoglobulin genes are generated during differentiation of B lymphocytes by joining gene segments. A mouse pre-B cell contains a functional immunoglobulin heavy-chain gene, but no light-chain gene. Although there is only one heavy-chain locus, there are two lightchain loci: κ and λ.It has been rep...

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Detalles Bibliográficos
Autores principales:	Berg, Jörg, Mcdowell, Mindy, Jäck, Hans-Martin, Wabl, Matthias
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 1990
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275820/ https://www.ncbi.nlm.nih.gov/pubmed/2136205 http://dx.doi.org/10.1155/1990/56014

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