Thymic Involution in Viable Motheaten (me(υ)) Mice is Associated with a Loss of Intrathymic Precursor Activity

Mice homozygous for the viable motheaten (me(υ)) allele manifest abnormalities in thymocytopoiesis, are severely immunodeficient, and develop autoimmune disorders early in life. Premature thymic involution occurs in me(υ)/me(υ) mice, and their bone marrow prothymocytes are unable to repopulate the t...

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Detalles Bibliográficos
Autores principales: Hayes, Sandra M., Shultz, Leonard D., Greiner, Dale L.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1992
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275861/
https://www.ncbi.nlm.nih.gov/pubmed/1627951
http://dx.doi.org/10.1155/1992/68954

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275861/
https://www.ncbi.nlm.nih.gov/pubmed/1627951
http://dx.doi.org/10.1155/1992/68954

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