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Self-Reactivity and the Expression of Memory Markers Vary Independently in MRL-Mp+/+ and MRL-Mp-lpr/lpr Mice

MRL-Mp-lpr/lpr mice contain phenotypically abnormal populations of T cells, and exhibit an SLE-like autoimmune disease in which autoantibodies are a prominent feature. We analyzed the phenotype and T-cell receptor Vß expression pattern in CD4(+) T cells of this mutant mouse strain to detect abnormal...

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Detalles Bibliográficos
Autores principales: Smyth, Lesley, Howell, Michelle, Crispe, I. Nicholas
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1992
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275871/
https://www.ncbi.nlm.nih.gov/pubmed/1343099
http://dx.doi.org/10.1155/1992/89109