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Self-Reactivity and the Expression of Memory Markers Vary Independently in MRL-Mp+/+ and MRL-Mp-lpr/lpr Mice
MRL-Mp-lpr/lpr mice contain phenotypically abnormal populations of T cells, and exhibit an SLE-like autoimmune disease in which autoantibodies are a prominent feature. We analyzed the phenotype and T-cell receptor Vß expression pattern in CD4(+) T cells of this mutant mouse strain to detect abnormal...
Autores principales: | Smyth, Lesley, Howell, Michelle, Crispe, I. Nicholas |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
1992
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275871/ https://www.ncbi.nlm.nih.gov/pubmed/1343099 http://dx.doi.org/10.1155/1992/89109 |
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