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Expression of The αβ T-Cell Receptor Is Necessary for The Generation of The Thymic Medulla

The architecture of the thymus of mice that congenitally fail to express the αβ T-cell receptor (TCRαβ) has been examined by immunohistology. In these mice, a defined mutation was introduced into the TCRc gene by homologous recombination. By using antibodies specific for cortical or medullary epithe...

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Detalles Bibliográficos
Autores principales: Palmer, Donald B., Viney, Joanne L., Ritter, Mary A., Hayday, Adrian C., Owen, Michael J.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1993
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275932/
https://www.ncbi.nlm.nih.gov/pubmed/8281032
http://dx.doi.org/10.1155/1993/56290