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Expression of λ and K Genes Can Occur in all B Cells and is Initiated Around the Same Pre-B-Cell Developmental Stage

Transgenic mice that carry a λ2 transgene under the control of the Vλ2 promoter and the Eλ2-4 enhancer (λ2Eλ mice) are described. A high proportion of B cells in the spleen and the bone marrow express the λ transgene on the cell membrane. λ2 protein is synthesized by all λ2Eλ-derived spleen B-cell h...

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Detalles Bibliográficos
Autores principales: Doglio, Lynn, Kim, Joo Yeun, Bozek, Grazyna, Storb, Ursula
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1994
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275945/
https://www.ncbi.nlm.nih.gov/pubmed/7620323
http://dx.doi.org/10.1155/1994/87352