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Expression of λ and K Genes Can Occur in all B Cells and is Initiated Around the Same Pre-B-Cell Developmental Stage
Transgenic mice that carry a λ2 transgene under the control of the Vλ2 promoter and the Eλ2-4 enhancer (λ2Eλ mice) are described. A high proportion of B cells in the spleen and the bone marrow express the λ transgene on the cell membrane. λ2 protein is synthesized by all λ2Eλ-derived spleen B-cell h...
Autores principales: | Doglio, Lynn, Kim, Joo Yeun, Bozek, Grazyna, Storb, Ursula |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
1994
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275945/ https://www.ncbi.nlm.nih.gov/pubmed/7620323 http://dx.doi.org/10.1155/1994/87352 |
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