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Differential Effects of X-Irradiation and Cyclosporin-A Administration on the Thymus with Respect to the Generation of Cyclosporin-A-Induced Autoimmunity

Cyclosporin A (CsA), a potent inhibitor of T-cell activation, has been shown to have several effects on thymocyte maturation, thymic stromal cells, and the generation of autoreactive T cells. In Lewis rats, the combination of lethal irradiation, syngeneic bone marrow transplantation, and a 4-week co...

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Detalles Bibliográficos
Autores principales: Beijleveld, Leo J.J., Damoiseaux, Jan G.M.C., Van Breda Vriesman, Peter J.C.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1995
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275949/
https://www.ncbi.nlm.nih.gov/pubmed/9700362
http://dx.doi.org/10.1155/1995/18495