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Differential Effects of X-Irradiation and Cyclosporin-A Administration on the Thymus with Respect to the Generation of Cyclosporin-A-Induced Autoimmunity
Cyclosporin A (CsA), a potent inhibitor of T-cell activation, has been shown to have several effects on thymocyte maturation, thymic stromal cells, and the generation of autoreactive T cells. In Lewis rats, the combination of lethal irradiation, syngeneic bone marrow transplantation, and a 4-week co...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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Hindawi Publishing Corporation
1995
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275949/ https://www.ncbi.nlm.nih.gov/pubmed/9700362 http://dx.doi.org/10.1155/1995/18495 |