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Somatic Mutations During an Immune Response in Xenopus Tadpoles

The tadpole B-cell repertoire is less diverse than that of the adult frog; their antibodies are of lower affinity and are less heterogenous. In order to determine whether this difference is due to a lack of or a reduced rate of somatic hypermutation, we analyzed and compared cDNA sequences utilizing...

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Detalles Bibliográficos
Autores principales: Wilson, Melanie, Marcuz, Anne, Du Pasquier, Louis
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1995
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275958/
https://www.ncbi.nlm.nih.gov/pubmed/8770561
http://dx.doi.org/10.1155/1995/38639