Correction of the TNF-LTα-Deficient Phenotype by Bone Marrow Transplantation

Mice with inactivated TNF-LTα genes have profound abnormalities of the immune system with hypoimmunoglobulinaemia, lack of lymph nodes, undifferentiated spleen, and defective Ig class switch. Transplantation of bone marrow cells from wild-type mice restored the synthesis of TNF, corrected the spleni...

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Detalles Bibliográficos
Autores principales: Ryffel, Bernhard, Hir, Michel Le, Müller, Mathias, Eugster, Hans-Pietro
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1998
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276018/
https://www.ncbi.nlm.nih.gov/pubmed/9814599
http://dx.doi.org/10.1155/1998/76963

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276018/
https://www.ncbi.nlm.nih.gov/pubmed/9814599
http://dx.doi.org/10.1155/1998/76963

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