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Adhesion of Immature and Mature T Cells Induces in Human Thymic Epithelial Cells (TEC) Activation of IL-6 Gene Trascription Factors (NF-κB And NF-IL6) and IL-6 Gene Expression : Role of αtβ1 and α6β4 Integrins

T cell precursors homed to thymus develop in close contact with stromal cells. Among them, thymic epithelial cells (TEC) are known to exert dominant roles in their survival and functional shaping. Key molecules mediating TEC/thymocytes interactions include cytokines and growth factors secreted by th...

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Detalles Bibliográficos
Autores principales: Fiorini, Emma, Marchisio, Pier Carlo, Scupoli, Maria Teresa, Poffe, Ornella, Tagliabue, Elda, Brentegani, Monica, Colombatti, Marco, Santini, Franscesco, Tridente, Giuseppe, Ramarli, Dunia
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276048/
https://www.ncbi.nlm.nih.gov/pubmed/11097212
http://dx.doi.org/10.1155/2000/48239