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Downregulated Expression of Ly-6-ThB on Developing T Cells Marks CD4(+)CD8(+) Subset Undergoing Selection in the Thymus
Interaction of TCRs on CD4(+)CD8(+) immature T cell with MHC-peptide complexes on stromal cells is required for positive and negative selection in the thymus. Identification and characterization of a subpopulation of CD4(+)CD8(+) thymocytes undergoing selection in the thymus will aid in understandin...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276067/ https://www.ncbi.nlm.nih.gov/pubmed/11589307 http://dx.doi.org/10.1155/2001/63451 |