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Downregulated Expression of Ly-6-ThB on Developing T Cells Marks CD4(+)CD8(+) Subset Undergoing Selection in the Thymus

Interaction of TCRs on CD4(+)CD8(+) immature T cell with MHC-peptide complexes on stromal cells is required for positive and negative selection in the thymus. Identification and characterization of a subpopulation of CD4(+)CD8(+) thymocytes undergoing selection in the thymus will aid in understandin...

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Detalles Bibliográficos
Autores principales: Reese, Justin T., Mehta, Hitesh, Chappell, Clay H., Bamezai, Anil.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276067/
https://www.ncbi.nlm.nih.gov/pubmed/11589307
http://dx.doi.org/10.1155/2001/63451