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Enforced Expression of Bcl-2 Selectively Perturbs Negative Selection of Dual Reactive Antibodies

We investigated the role of apoptosis in the development of B cell memory by analyzing the (p-azophenylarsonate) Ars response in a line of A strain mice in which expression of human Bcl-2 was enforced in the B cell compartment. Previous studies of the Ars immune response in these A. Bcl-2 mice, demo...

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Detalles Bibliográficos
Autores principales: Notidis, Evangelia, Hande, Shailaja, Manser, Tim
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276081/
https://www.ncbi.nlm.nih.gov/pubmed/11785672
http://dx.doi.org/10.1155/2001/83595