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Characterization of the Rapid Proteolytic Shedding of Murine L-Selectin

The structural requirements for L-selectin shedding were studied in murine leukocytes. Upon activation, L-selectin on both lymphocytes and neutrophils undergoes cleavage by a membrane metalloprotease, resulting in the generation of a soluble ectodomain and a membrane- retained 6 kD fragment. Radioch...

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Detalles Bibliográficos
Autores principales: Zhao, Li-Chao, Edgar, John B., Dailey, Morris O.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276085/
https://www.ncbi.nlm.nih.gov/pubmed/11785676
http://dx.doi.org/10.1155/2001/91831