The Dynamics of Germinal Centre Selection as Measured by Graph-Theoretical Analysis of Mutational Lineage Trees

We have developed a rigorous graph-theoretical algorithm for quantifying the shape properties of mutational lineage trees. We show that information about the dynamics of hypermutation and antigen-driven clonal selection during the humoral immune response is contained in the shape of mutational linea...

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Detalles Bibliográficos
Autores principales: Dunn-Walters, Deborah K., Belelovsky, Alex, Edelman, Hanna, Banerjee, Monica, Mehr, Ramit
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2002
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276115/
https://www.ncbi.nlm.nih.gov/pubmed/15144020
http://dx.doi.org/10.1080/10446670310001593541

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276115/
https://www.ncbi.nlm.nih.gov/pubmed/15144020
http://dx.doi.org/10.1080/10446670310001593541

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