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Careful adjustment of Epo non-viral gene therapy for β-thalassemic anaemia treatment

BACKGROUND: In situ production of a secreted therapeutic protein is one of the major gene therapy applications. Nevertheless, the plasmatic secretion peak of transgenic protein may be deleterious in many gene therapy applications including Epo gene therapy. Epo gene transfer appears to be a promisin...

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Detalles Bibliográficos
Autores principales: Fabre, Emmanuelle E, Bigey, Pascal, Beuzard, Yves, Scherman, Daniel, Payen, Emmanuel
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276190/
https://www.ncbi.nlm.nih.gov/pubmed/18334017
http://dx.doi.org/10.1186/1479-0556-6-10