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Careful adjustment of Epo non-viral gene therapy for β-thalassemic anaemia treatment
BACKGROUND: In situ production of a secreted therapeutic protein is one of the major gene therapy applications. Nevertheless, the plasmatic secretion peak of transgenic protein may be deleterious in many gene therapy applications including Epo gene therapy. Epo gene transfer appears to be a promisin...
Autores principales: | Fabre, Emmanuelle E, Bigey, Pascal, Beuzard, Yves, Scherman, Daniel, Payen, Emmanuel |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276190/ https://www.ncbi.nlm.nih.gov/pubmed/18334017 http://dx.doi.org/10.1186/1479-0556-6-10 |
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