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Real-time PCR/MCA assay using fluorescence resonance energy transfer for the genotyping of resistance related DHPS-540 mutations in Plasmodium falciparum

BACKGROUND: Sulphadoxine-pyrimethamine has been abandoned as first- or second-line treatment by most African malaria endemic countries in favour of artemisinin-based combination treatments, but the drug is still used as intermittent preventive treatment during pregnancy. However, resistance to sulph...

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Detalles Bibliográficos
Autores principales: Mens, Petra F, van Overmeir, Chantal, Bonnet, Maryline, Dujardin, Jean-Claude, d'Alessandro, Umberto
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276220/
https://www.ncbi.nlm.nih.gov/pubmed/18346279
http://dx.doi.org/10.1186/1475-2875-7-48