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Identification of a novel resistance (E40F) and compensatory (K43E) substitution in HIV-1 reverse transcriptase
BACKGROUND: HIV-1 nucleoside reverse transcriptase inhibitors (NRTIs) have been used in the clinic for over twenty years. Interestingly, the complete resistance pattern to this class has not been fully elucidated. Novel mutations in RT appearing during treatment failure are still being identified. T...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276231/ https://www.ncbi.nlm.nih.gov/pubmed/18271957 http://dx.doi.org/10.1186/1742-4690-5-20 |