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Small interfering RNA targeting CDC25B inhibits liver tumor growth in vitro and in vivo
BACKGROUND: Using gene expression profiling, we previously identified CDC25B to be significantly highly expressed in hepatocellular carcinoma (HCC) compared to non-tumor liver. CDC25B is a cell cycle-activating phosphatase that positively regulates the activity of cyclin-dependent kinases, and is ov...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276234/ https://www.ncbi.nlm.nih.gov/pubmed/18269767 http://dx.doi.org/10.1186/1476-4598-7-19 |