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Small interfering RNA targeting CDC25B inhibits liver tumor growth in vitro and in vivo

BACKGROUND: Using gene expression profiling, we previously identified CDC25B to be significantly highly expressed in hepatocellular carcinoma (HCC) compared to non-tumor liver. CDC25B is a cell cycle-activating phosphatase that positively regulates the activity of cyclin-dependent kinases, and is ov...

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Detalles Bibliográficos
Autores principales: Yan, Xinrui, Chua, Mei-Sze, He, Jing, So, Samuel K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276234/
https://www.ncbi.nlm.nih.gov/pubmed/18269767
http://dx.doi.org/10.1186/1476-4598-7-19