Acetylation Regulates WRN Catalytic Activities and Affects Base Excision DNA Repair

BACKGROUND: The Werner protein (WRN), defective in the premature aging disorder Werner syndrome, participates in a number of DNA metabolic processes, and we have been interested in the possible regulation of its function in DNA repair by post-translational modifications. Acetylation mediated by hist...

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Detalles Bibliográficos
Autores principales: Muftuoglu, Meltem, Kusumoto, Rika, Speina, Elzbieta, Beck, Gad, Cheng, Wen-Hsing, Bohr, Vilhelm A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276247/
https://www.ncbi.nlm.nih.gov/pubmed/18398454
http://dx.doi.org/10.1371/journal.pone.0001918

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276247/
https://www.ncbi.nlm.nih.gov/pubmed/18398454
http://dx.doi.org/10.1371/journal.pone.0001918

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