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Nature of Protein Family Signatures: Insights from Singular Value Analysis of Position-Specific Scoring Matrices
Position-specific scoring matrices (PSSMs) are useful for detecting weak homology in protein sequence analysis, and they are thought to contain some essential signatures of the protein families. In order to elucidate what kind of ingredients constitute such family-specific signatures, we apply singu...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276316/ https://www.ncbi.nlm.nih.gov/pubmed/18398479 http://dx.doi.org/10.1371/journal.pone.0001963 |