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Nature of Protein Family Signatures: Insights from Singular Value Analysis of Position-Specific Scoring Matrices

Position-specific scoring matrices (PSSMs) are useful for detecting weak homology in protein sequence analysis, and they are thought to contain some essential signatures of the protein families. In order to elucidate what kind of ingredients constitute such family-specific signatures, we apply singu...

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Detalles Bibliográficos
Autores principales: Kinjo, Akira R., Nakamura, Haruki
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276316/
https://www.ncbi.nlm.nih.gov/pubmed/18398479
http://dx.doi.org/10.1371/journal.pone.0001963