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Quantitative Single-letter Sequencing: a method for simultaneously monitoring numerous known allelic variants in single DNA samples

BACKGROUND: Pathogens such as fungi, bacteria and especially viruses, are highly variable even within an individual host, intensifying the difficulty of distinguishing and accurately quantifying numerous allelic variants co-existing in a single nucleic acid sample. The majority of currently availabl...

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Detalles Bibliográficos
Autores principales: Monsion, Baptiste, Duborjal, Hervé, Blanc, Stéphane
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276495/
https://www.ncbi.nlm.nih.gov/pubmed/18291029
http://dx.doi.org/10.1186/1471-2164-9-85