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Inducing apoptosis of human colon cancer cells by an IGF-I D domain analogue peptide

BACKGROUND: The resistance of tumour cells to apoptosis is a major contributor to the limited effectiveness of chemotherapies. Insulin-like growth factor I (IGF-I) has potential to protect cancer cells from variety of apoptotic challenges. This study was carried out to investigate the effect of a no...

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Detalles Bibliográficos
Autores principales: Yang, Shi Yu, Sales, Kevin M, Fuller, Barry J, Seifalian, Alexander M, Winslet, Marc C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276513/
https://www.ncbi.nlm.nih.gov/pubmed/18261206
http://dx.doi.org/10.1186/1476-4598-7-17