Sequence Effect of Self-Assembling Peptides on the Complexation and In Vitro Delivery of the Hydrophobic Anticancer Drug Ellipticine

A special class of self-assembling peptides has been found to be capable of stabilizing the hydrophobic anticancer agent ellipticine in aqueous solution. Here we study the effect of peptide sequence on the complex formation and its anticancer activity in vitro. Three peptides, EAK16-II, EAK16-IV and...

Descripción completa

Detalles Bibliográficos
Autores principales: Fung, Shan Yu, Yang, Hong, Chen, P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276859/
https://www.ncbi.nlm.nih.gov/pubmed/18398476
http://dx.doi.org/10.1371/journal.pone.0001956

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276859/
https://www.ncbi.nlm.nih.gov/pubmed/18398476
http://dx.doi.org/10.1371/journal.pone.0001956

Ejemplares similares