Receptor Guided 3D-QSAR: A Useful Approach for Designing of IGF-1R Inhibitors

Research by other investigators has established that insulin-like growth factor‐1 receptor (IGF-1R) is a key oncological target, and that derivatives of 1, 3-disubstituted-imidazo[1,5-α] pyrazine are potent IGF-1R inhibitors. In this paper, we report on our three-dimensional quantitative structure a...

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Detalles Bibliográficos
Autores principales: Muddassar, M., Pasha, F. A., Chung, H. W., Yoo, K. H., Oh, C. H., Cho, S. J.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276912/
https://www.ncbi.nlm.nih.gov/pubmed/18385815
http://dx.doi.org/10.1155/2008/837653

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276912/
https://www.ncbi.nlm.nih.gov/pubmed/18385815
http://dx.doi.org/10.1155/2008/837653

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