Substrate-induced DNA strand misalignment during catalytic cycling by DNA polymerase λ

The simple deletion of nucleotides is common in many organisms. It can be advantageous when it activates genes beneficial to microbial survival in adverse environments, and deleterious when it mutates genes relevant to survival, cancer or degenerative diseases. The classical idea is that simple dele...

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Detalles Bibliográficos
Autores principales: Bebenek, Katarzyna, Garcia-Diaz, Miguel, Foley, Meredith C, Pedersen, Lars C, Schlick, Tamar, Kunkel, Thomas A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Scientific Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2278112/
https://www.ncbi.nlm.nih.gov/pubmed/18369368
http://dx.doi.org/10.1038/embor.2008.33

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2278112/
https://www.ncbi.nlm.nih.gov/pubmed/18369368
http://dx.doi.org/10.1038/embor.2008.33

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