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Design of a zinc finger protein binding a sequence upstream of the A20 gene

BACKGROUND: Artificial transcription factors (ATFs) are composed of DNA-binding and functional domains. These domains can be fused together to create proteins that can bind a chosen DNA sequence. To construct a valid ATF, it is necessary to design suitable DNA-binding and functional domains. The Cys...

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Detalles Bibliográficos
Autores principales: Wei, Yong, Ying, Dajun, Hou, Chunli, Cui, Xiaoping, Zhu, Chuhong
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2278136/
https://www.ncbi.nlm.nih.gov/pubmed/18366681
http://dx.doi.org/10.1186/1472-6750-8-28