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Design of a zinc finger protein binding a sequence upstream of the A20 gene
BACKGROUND: Artificial transcription factors (ATFs) are composed of DNA-binding and functional domains. These domains can be fused together to create proteins that can bind a chosen DNA sequence. To construct a valid ATF, it is necessary to design suitable DNA-binding and functional domains. The Cys...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2278136/ https://www.ncbi.nlm.nih.gov/pubmed/18366681 http://dx.doi.org/10.1186/1472-6750-8-28 |