Regulation of the cd38 promoter in human airway smooth muscle cells by TNF-α and dexamethasone

BACKGROUND: CD38 is expressed in human airway smooth muscle (HASM) cells, regulates intracellular calcium, and its expression is augmented by tumor necrosis factor alpha (TNF-α). CD38 has a role in airway hyperresponsiveness, a hallmark of asthma, since deficient mice develop attenuated airway hyper...

Descripción completa

Detalles Bibliográficos
Autores principales: Tirumurugaan, Krishnaswamy G, Kang, Bit Na, Panettieri, Reynold A, Foster, Douglas N, Walseth, Timothy F, Kannan, Mathur S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2278140/
https://www.ncbi.nlm.nih.gov/pubmed/18341691
http://dx.doi.org/10.1186/1465-9921-9-26

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2278140/
https://www.ncbi.nlm.nih.gov/pubmed/18341691
http://dx.doi.org/10.1186/1465-9921-9-26

Ejemplares similares