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Regulation of the cd38 promoter in human airway smooth muscle cells by TNF-α and dexamethasone
BACKGROUND: CD38 is expressed in human airway smooth muscle (HASM) cells, regulates intracellular calcium, and its expression is augmented by tumor necrosis factor alpha (TNF-α). CD38 has a role in airway hyperresponsiveness, a hallmark of asthma, since deficient mice develop attenuated airway hyper...
Autores principales: | Tirumurugaan, Krishnaswamy G, Kang, Bit Na, Panettieri, Reynold A, Foster, Douglas N, Walseth, Timothy F, Kannan, Mathur S |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2278140/ https://www.ncbi.nlm.nih.gov/pubmed/18341691 http://dx.doi.org/10.1186/1465-9921-9-26 |
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