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Immature Cryopreserved Ovary Restores Puberty and Fertility in Mice without Alteration of Epigenetic Marks

BACKGROUND: Progress in oncology could improve survival rate in children, but would probably lead to impaired fertility and puberty. In pre-pubertal girls, the only therapeutic option is the cryopreservation of one ovary. Three births have been reported after reimplantation of cryopreserved mature o...

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Detalles Bibliográficos
Autores principales: Sauvat, Frédérique, Capito, Carmen, Sarnacki, Sabine, Poirot, Catherine, Bachelot, Anne, Meduri, Geri, Dandolo, Luisa, Binart, Nadine
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2278373/
https://www.ncbi.nlm.nih.gov/pubmed/18414667
http://dx.doi.org/10.1371/journal.pone.0001972