Chronic morphine administration enhances nociceptive sensitivity and local cytokine production after incision

BACKGROUND -: The chronic use of opioids prior to surgery leads to lowered pain thresholds and exaggerated pain levels after these procedures. Several mechanisms have been proposed to explain this heightened sensitivity commonly termed opioid-induced hyperalgesia (OIH). Most of these proposed mechan...

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Detalles Bibliográficos
Autores principales: Liang, DeYong, Shi, Xiaoyou, Qiao, Yanli, Angst, Martin S, Yeomans, David C, Clark, J David
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2279109/
https://www.ncbi.nlm.nih.gov/pubmed/18294378
http://dx.doi.org/10.1186/1744-8069-4-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2279109/
https://www.ncbi.nlm.nih.gov/pubmed/18294378
http://dx.doi.org/10.1186/1744-8069-4-7

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