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Chronic morphine administration enhances nociceptive sensitivity and local cytokine production after incision
BACKGROUND -: The chronic use of opioids prior to surgery leads to lowered pain thresholds and exaggerated pain levels after these procedures. Several mechanisms have been proposed to explain this heightened sensitivity commonly termed opioid-induced hyperalgesia (OIH). Most of these proposed mechan...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2279109/ https://www.ncbi.nlm.nih.gov/pubmed/18294378 http://dx.doi.org/10.1186/1744-8069-4-7 |