A novel brain-enriched E3 ubiquitin ligase RNF182 is up regulated in the brains of Alzheimer's patients and targets ATP6V0C for degradation

BACKGROUND: Alterations in multiple cellular pathways contribute to the development of chronic neurodegeneration such as a sporadic Alzheimer's disease (AD). These, in turn, involve changes in gene expression, amongst which are genes regulating protein processing and turnover such as the compon...

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Detalles Bibliográficos
Autores principales: Liu, Qing Yan, Lei, Joy X, Sikorska, Marianna, Liu, Rugao
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2279130/
https://www.ncbi.nlm.nih.gov/pubmed/18298843
http://dx.doi.org/10.1186/1750-1326-3-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2279130/
https://www.ncbi.nlm.nih.gov/pubmed/18298843
http://dx.doi.org/10.1186/1750-1326-3-4

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