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The Apoptosome: Emerging Insights and New Potential Targets for Drug Design

Apoptosis plays a crucial role in tissue homeostasis, development and many diseases. The relevance of Apaf1, the molecular core of apoptosome, has been underlined in mitochondria-dependent apoptosis, which according to a growing body of evidence, is involved in various pathologies where the equilibr...

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Detalles Bibliográficos
Autores principales: D’Amelio, Marcello, Tino, Elisa, Cecconi, Francesco
Formato: Texto
Lenguaje:English
Publicado: Springer US 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2279152/
https://www.ncbi.nlm.nih.gov/pubmed/17674158
http://dx.doi.org/10.1007/s11095-007-9396-z