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The Apoptosome: Emerging Insights and New Potential Targets for Drug Design
Apoptosis plays a crucial role in tissue homeostasis, development and many diseases. The relevance of Apaf1, the molecular core of apoptosome, has been underlined in mitochondria-dependent apoptosis, which according to a growing body of evidence, is involved in various pathologies where the equilibr...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer US
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2279152/ https://www.ncbi.nlm.nih.gov/pubmed/17674158 http://dx.doi.org/10.1007/s11095-007-9396-z |