Cargando…

The Interferon Response Inhibits HIV Particle Production by Induction of TRIM22

Treatment of human cells with Type 1 interferons restricts HIV replication. Here we report that the tripartite motif protein TRIM22 is a key mediator. We used transcriptional profiling to identify cellular genes that were induced by interferon treatment and identified TRIM22 as one of the most stron...

Descripción completa

Detalles Bibliográficos
Autores principales: Barr, Stephen D., Smiley, James R., Bushman, Frederic D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2279259/
https://www.ncbi.nlm.nih.gov/pubmed/18389079
http://dx.doi.org/10.1371/journal.ppat.1000007