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The Interferon Response Inhibits HIV Particle Production by Induction of TRIM22
Treatment of human cells with Type 1 interferons restricts HIV replication. Here we report that the tripartite motif protein TRIM22 is a key mediator. We used transcriptional profiling to identify cellular genes that were induced by interferon treatment and identified TRIM22 as one of the most stron...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2279259/ https://www.ncbi.nlm.nih.gov/pubmed/18389079 http://dx.doi.org/10.1371/journal.ppat.1000007 |