The Interferon Response Inhibits HIV Particle Production by Induction of TRIM22

Treatment of human cells with Type 1 interferons restricts HIV replication. Here we report that the tripartite motif protein TRIM22 is a key mediator. We used transcriptional profiling to identify cellular genes that were induced by interferon treatment and identified TRIM22 as one of the most stron...

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Detalles Bibliográficos
Autores principales: Barr, Stephen D., Smiley, James R., Bushman, Frederic D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2279259/
https://www.ncbi.nlm.nih.gov/pubmed/18389079
http://dx.doi.org/10.1371/journal.ppat.1000007

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