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Adenylyl Cyclase α and cAMP Signaling Mediate Plasmodium Sporozoite Apical Regulated Exocytosis and Hepatocyte Infection

Malaria starts with the infection of the liver of the host by Plasmodium sporozoites, the parasite form transmitted by infected mosquitoes. Sporozoites migrate through several hepatocytes by breaching their plasma membranes before finally infecting one with the formation of an internalization vacuol...

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Detalles Bibliográficos
Autores principales: Ono, Takeshi, Cabrita-Santos, Laura, Leitao, Ricardo, Bettiol, Esther, Purcell, Lisa A., Diaz-Pulido, Olga, Andrews, Lucy B., Tadakuma, Takushi, Bhanot, Purnima, Mota, Maria M., Rodriguez, Ana
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2279260/
https://www.ncbi.nlm.nih.gov/pubmed/18389080
http://dx.doi.org/10.1371/journal.ppat.1000008