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Adenylyl Cyclase α and cAMP Signaling Mediate Plasmodium Sporozoite Apical Regulated Exocytosis and Hepatocyte Infection
Malaria starts with the infection of the liver of the host by Plasmodium sporozoites, the parasite form transmitted by infected mosquitoes. Sporozoites migrate through several hepatocytes by breaching their plasma membranes before finally infecting one with the formation of an internalization vacuol...
Autores principales: | Ono, Takeshi, Cabrita-Santos, Laura, Leitao, Ricardo, Bettiol, Esther, Purcell, Lisa A., Diaz-Pulido, Olga, Andrews, Lucy B., Tadakuma, Takushi, Bhanot, Purnima, Mota, Maria M., Rodriguez, Ana |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2279260/ https://www.ncbi.nlm.nih.gov/pubmed/18389080 http://dx.doi.org/10.1371/journal.ppat.1000008 |
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