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Strain-Specific Virulence Phenotypes of Streptococcus pneumoniae Assessed Using the Chinchilla laniger Model of Otitis Media

BACKGROUND: Streptococcus pneumoniae [Sp] infection is associated with local and systemic disease. Our current understanding of the differential contributions of genetic strain variation, serotype, and host response to disease phenotype is incomplete. Using the chinchilla model of otitis media [OM]...

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Detalles Bibliográficos
Autores principales: Forbes, Michael L., Horsey, Edward, Hiller, N. Luisa, Buchinsky, Farrel J., Hayes, Jay D., Compliment, James M., Hillman, Todd, Ezzo, Suzanne, Shen, Kai, Keefe, Randy, Barbadora, Karen, Post, J. Christopher, Hu, Fen Ze, Ehrlich, Garth D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2279396/
https://www.ncbi.nlm.nih.gov/pubmed/18398481
http://dx.doi.org/10.1371/journal.pone.0001969