A2 isoform of mammalian translation factor eEF1A displays increased tyrosine phosphorylation and ability to interact with different signalling molecules

The eEF1A1 and eEF1A2 isoforms of translation elongation factor 1A have 98% similarity and perform the same protein synthesis function catalyzing codon-dependent binding of aminoacyl-tRNA to 80S ribosome. However, the isoforms apparently play different non-canonical roles in apoptosis and cancer dev...

Descripción completa

Detalles Bibliográficos
Autores principales: Panasyuk, Ganna, Nemazanyy, Ivan, Filonenko, Valeriy, Negrutskii, Boris, El'skaya, Anna V.
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2008
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2279807/
https://www.ncbi.nlm.nih.gov/pubmed/17936057
http://dx.doi.org/10.1016/j.biocel.2007.08.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2279807/
https://www.ncbi.nlm.nih.gov/pubmed/17936057
http://dx.doi.org/10.1016/j.biocel.2007.08.014

Ejemplares similares