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Rarity of Somatic Mutation and Frequency of Normal Sequence Variation Detected in Sporadic Colon Adenocarcinoma Using High-Throughput cDNA Sequencing

We performed high-throughput cDNA sequencing in colorectal adenocarcinoma and matching normal colorectal epithelium. All six hundred three genes in the UCSC database that were expressed in colon cancers and contained open reading frames of 1000 nucleotides or less were selected for study (total base...

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Detalles Bibliográficos
Autores principales: Kan, Takatsugu, Paun, Bogdan C., Mori, Yuriko, Sato, Fumiaki, Jin, Zhe, Hamilton, James P., Ito, Tetsuo, Cheng, Yulan, David, Stefan, Olaru, Alexandru V., Yang, Jian, Agarwal, Rachana, Abraham, John M., Meltzer, Stephen J.
Formato: Texto
Lenguaje:English
Publicado: Libertas Academica 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2287164/
https://www.ncbi.nlm.nih.gov/pubmed/18389087