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Intracellular delivery of peptides via association with ubiquitin or SUMO-1 coupled to protein transduction domains

BACKGROUND: We previously developed small hybrid proteins consisting of SUMO-1 linked to an heptapeptide fused to the Tat protein transduction domain (PTD). The heptapeptide motif was selected from a library of random sequences to specifically bind HIV-1 regulatory proteins Tat or Rev. These constru...

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Detalles Bibliográficos
Autores principales: Vitte, Anne-Laure, Jalinot, Pierre
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2287181/
https://www.ncbi.nlm.nih.gov/pubmed/18312666
http://dx.doi.org/10.1186/1472-6750-8-24