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Intracellular delivery of peptides via association with ubiquitin or SUMO-1 coupled to protein transduction domains
BACKGROUND: We previously developed small hybrid proteins consisting of SUMO-1 linked to an heptapeptide fused to the Tat protein transduction domain (PTD). The heptapeptide motif was selected from a library of random sequences to specifically bind HIV-1 regulatory proteins Tat or Rev. These constru...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2287181/ https://www.ncbi.nlm.nih.gov/pubmed/18312666 http://dx.doi.org/10.1186/1472-6750-8-24 |