Correlation between β-catenin mutations and expression of Wnt-signaling target genes in hepatocellular carcinoma

Aberrant Wnt-signaling caused by mutants of β-catenin, a key regulator of the canonical Wnt-signaling pathway, is frequently detected in cancer. Only recently, it was suggested that in hepatocellular carcinoma (HCC) the expression of the target gene glutamine synthetase (GS) is a highly reliable mar...

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Detalles Bibliográficos
Autores principales: Austinat, Madeleine, Dunsch, Ruediger, Wittekind, Christian, Tannapfel, Andrea, Gebhardt, Rolf, Gaunitz, Frank
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2287186/
https://www.ncbi.nlm.nih.gov/pubmed/18282277
http://dx.doi.org/10.1186/1476-4598-7-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2287186/
https://www.ncbi.nlm.nih.gov/pubmed/18282277
http://dx.doi.org/10.1186/1476-4598-7-21

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